Article
Regulation of a yeast HSP70 gene by a cAMP responsive transcriptional control element.
The EMBO journal - 1 Aug 1990
Boorstein W R, Craig E A
Abstract excerpt
HSP70 genes exhibit complex regulation in response to stress and a variety of cellular and developmental events. The SSA3 HSP70 gene of Saccharomyces cerevisiae is activated at the transcriptional level under conditions of nutrient limitation. Analysis of deletions revealed that cis-acting DNA sequences present immediately upstream and downstream of the previously identified heat shock elements (UASHS) mediate...
Topics
- 1-Methyl-3-isobutylxanthine
- Base Sequence
- Chromosome Deletion
- Cyclic AMP
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Heat-Shock Proteins
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Protein Kinases
