Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants in the RAB7L1 and SLC41A1 genes of the PARK16 locus in Chinese Parkinson's disease patients.

The International journal of neuroscience - 1 Nov 2011

Yan Yaping, Tian Jun, Mo Xiaoyun, Zhao Guohua, Yin Xinzhen, Pu Jiali, Zhang Baorong

Abstract excerpt

We performed direct DNA sequencing of the RAB7L1 and SLC41A1 genes within the PARK16 locus in 205 Chinese Parkinson's disease (PD) patients. Three novel heterozygous variants were identified in SLC41A1: c.436A > G (causing p.Lys146Glu), c.1440A > G (causing p.Pro480Pro), and c.552 + 50G > A. These three variants were not present in any of the 210 genetically unrelated healthy controls of the same ethnic origin....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Asian People

Share to Cation Transport Proteins

Share to Parkinson Disease

Share to rab GTP-Binding Proteins

Share to rab7 GTP-Binding Proteins

Share to Young Adult

Source

Identifiers

PMID: 21812739
DOI: 10.3109/00207454.2011.598983

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants in the RAB7L1 and SLC41A1 genes of the PARK16 locus in Chinese Parkinson's disease patients.PMID 21812739Read ↗

Genetic variability at the PARK16 locus.Semantic proximity Read ↗

Association between PARK16 and Parkinson's disease in the Han Chinese population: a meta-analysis.Semantic proximity Read ↗

Genetic analysis of SLC41A1 in Chinese Parkinson's disease patients.Semantic proximity Read ↗

Fine mapping and resequencing of the PARK16 locus in Parkinson's disease.Semantic proximity Read ↗

Associations of rs823128, rs1572931, and rs823156 polymorphisms with reduced Parkinson's disease risks.Semantic proximity Read ↗

Association between PARK16 gene polymorphisms and susceptibility of Parkinson's disease in a Chinese population.Semantic proximity Read ↗

Association between rs823128 polymorphism and the risk of Parkinson's disease: A meta-analysis.Semantic proximity Read ↗

RAB7L1 promoter polymorphism and risk of Parkinson's disease; a case-control study.Semantic proximity Read ↗

An association between the PARK16 locus and Parkinson's disease in a cohort from eastern China.Semantic proximity Read ↗

Analysis of Lrrk2 R1628P as a risk factor for Parkinson's disease.Semantic proximity Read ↗

LRRK2 R1628P increases risk of Parkinson's disease: replication evidence.Semantic proximity Read ↗

Analysis of GWAS-linked loci in Parkinson disease reaffirms PARK16 as a susceptibility locus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.