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Article

Relative efficiency of trend tests with misspecified genetic models in stratified analyses of case-control or cohort data.

Human heredity - 1 Jan 2011

Sitlani Colleen M, McKnight Barbara

Abstract excerpt

BACKGROUND/AIMS: Genetic single-nucleotide polymorphism (SNP) data are often analyzed using trend tests that rely on a specific assumption about the way that disease frequency varies across genotypes, but the validity of this assumption is not typically known. We explore the relative efficiency of trend tests in which the assumed model may or may not correspond to the true genetic model. METHODS: We derive...

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Identifiers

PMID: 21811075
DOI: 10.1159/000328858
PMCID: PMC3190174

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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