Article
Genome-wide survey of yeast mutations leading to activation of the yeast cell integrity MAPK pathway: novel insights into diverse MAPK outcomes.
BMC genomics - 2 Aug 2011
Arias Patricia, Díez-Muñiz Sonia, García Raúl, Nombela César, Rodríguez-Peña José M, Arroyo Javier
Abstract excerpt
BACKGROUND: The yeast cell wall integrity mitogen-activated protein kinase (CWI-MAPK) pathway is the main regulator of adaptation responses to cell wall stress in yeast. Here, we adopt a genomic approach to shed light on two aspects that are only partially understood, namely, the characterization of the gene functional catalog associated with CWI pathway activation and the extent to which MAPK activation...
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