Article
The sequential activation of the yeast HOG and SLT2 pathways is required for cell survival to cell wall stress.
Molecular biology of the cell - 1 Mar 2008
Bermejo Clara, Rodríguez Estefanía, García Raúl, Rodríguez-Peña Jose M, Rodríguez de la Concepción María L, Rivas Carmen, Arias Patricia, Nombela César, Posas Francesc, Arroyo Javier
Abstract excerpt
Yeast mitogen-activated protein kinase (MAPK) signaling pathways transduce external stimuli into cellular responses very precisely. The MAPKs Slt2/Mpk1 and Hog1 regulate transcriptional responses of adaptation to cell wall and osmotic stresses, respectively. Unexpectedly, we observe that the activation of a cell wall integrity (CWI) response to the cell wall damage caused by zymolyase (beta-1,3 glucanase)...
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