Article
Characterization of sensor-specific stress response by transcriptional profiling of wsc1 and mid2 deletion strains and chimeric sensors in Saccharomyces cerevisiae.
Omics : a journal of integrative biology - 1 Dec 2010
Bermejo Clara, García Raúl, Straede Andrea, Rodríguez-Peña José M, Nombela César, Heinisch Jürgen J, Arroyo Javier
Abstract excerpt
Cell wall stress in the model yeast Saccharomyces cerevisiae is known to trigger an adaptive transcriptional response. This response is mediated by a specific MAPK cell wall integrity (CWI) signal transduction pathway and affects the expression of many genes whose products are involved in the remodeling of the cellular envelope. Cell wall damage is detected mainly by Wsc1 and Mid2, which are the dominant sensors...
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