Article
Genome-wide analysis of the response to cell wall mutations in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry - 30 May 2003
Lagorce Arnaud, Hauser Nicole C, Labourdette Delphine, Rodriguez Cristina, Martin-Yken Helene, Arroyo Javier, Hoheisel Jörg D, François Jean
Abstract excerpt
Perturbations of the yeast cell wall trigger a repair mechanism that reconfigures its molecular structure to preserve cell integrity. To investigate this mechanism, we compared the global gene expression in five mutant strains, each bearing a mutation (i.e. fks1, kre6, mnn9, gas1, and knr4 mutants) that affects in a different manner the cell wall construction. Altogether, 300 responsive genes were kept based on...
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