Article
New insights into inflammatory bowel disease pathophysiology: paving the way for novel therapeutic targets.
Current drug targets - 1 May 2008
Stefanelli Tommaso, Malesci Alberto, Repici Alessandro, Vetrano Stefania, Danese Silvio
Abstract excerpt
The etiopathogenesis of Crohn's disease (CD) and ulcerative Colitis (UC), the two major forms of inflammatory bowel disease (IBD), is still unknown. Although the exact cause and mechanisms of both IBD have yet to be completely understood, it is widely accepted that both CD and UC result from an inappropriate immune response that occurs in genetically susceptible individuals as the result of a complex interaction...
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