Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RUNX transcription factors: association with pediatric asthma and modulated by maternal smoking.

American journal of physiology. Lung cellular and molecular physiology - 1 Nov 2011

Haley Kathleen J, Lasky-Su Jessica, Manoli Sara E, Smith Lacey A, Shahsafaei Aliakbar, Weiss Scott T, Tantisira Kelan

Abstract excerpt

Intrauterine smoke exposure (IUS) is a strong risk factor for development of airways responsiveness and asthma in childhood. Runt-related transcription factors (RUNX1-3) have critical roles in immune system development and function. We hypothesized that genetic variations in RUNX1 would be associated with airway responsiveness in asthmatic children and that this association would be modified by IUS. Family-based...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma
Share to Core Binding Factor Alpha 2 Subunit

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Methacholine Chloride

Share to Prenatal Exposure Delayed Effects

Share to Real-Time Polymerase Chain Reaction

Share to Smoking

Share to Tobacco Smoke Pollution

Source

Open in PubMed Open full text

Identifiers

PMID: 21803869
DOI: 10.1152/ajplung.00348.2010
PMCID: PMC3213989

Genes

RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RUNX transcription factors: association with pediatric asthma and modulated by maternal smoking.PMID 21803869Read ↗

Intrauterine Smoke Exposure, microRNA Expression during Human Lung Development, and Childhood AsthmaSemantic proximity Read ↗

The interaction of glutathione S-transferase M1-null variants with tobacco smoke exposure and the development of childhood asthma.Semantic proximity Read ↗

In utero exposures to mint-flavored JUUL aerosol impair lung development and aggravate house dust mite-induced asthma in adult offspring miceSemantic proximity Read ↗

Prenatal environmental tobacco smoke exposure increases allergic asthma risk with methylation changes in miceSemantic proximity Read ↗

Genetic influences on asthma susceptibility in the developing lung.Semantic proximity Read ↗

Sex-Specific Alterations of the Lung Transcriptome at Birth in Mouse Offspring Prenatally Exposed to Vanilla-Flavored E-Cigarette Aerosols and Enhanced Susceptibility to AsthmaSemantic proximity Read ↗

Transient early wheeze and lung function in early childhood associated with chronic obstructive pulmonary disease genes.Semantic proximity Read ↗

Second-hand smoke and NFE2L2 genotype interaction increases paediatric asthma risk and severity.Semantic proximity Read ↗

A role for Wnt signaling genes in the pathogenesis of impaired lung function in asthma.Semantic proximity Read ↗

Paternal Tobacco Smoke Correlated to Offspring Asthma and Prenatal Epigenetic ProgrammingSemantic proximity Read ↗

Epigenetics of hyper-responsiveness to allergen challenge following intrauterine growth retardation rat.Semantic proximity Read ↗

Epigenetic inheritance of fetal genes in allergic asthmaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.