Article
Epigenetics of hyper-responsiveness to allergen challenge following intrauterine growth retardation rat.
Respiratory research - 13 Nov 2014
Xu Xue-Feng, Hu Qiong-Yao, Liang Ling-Fang, Wu Lei, Gu Wei-Zhong, Tang Li-Li, Fu Lin-Chen, Du Li-Zhong
Abstract excerpt
BACKGROUND: Epidemiological studies have revealed that intrauterine growth retardation (IUGR) or low birth weight is linked to the later development of asthma. Epigenetic regulatory mechanisms play an important role in the fetal origins of adult disease. However, little is known regarding the correlation between epigenetic regulation and the development of asthma following IUGR. METHODS: An IUGR and ovalbumin...
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