Article
Genetic influences on asthma susceptibility in the developing lung.
American journal of respiratory cell and molecular biology - 1 Dec 2010
Carpe Nicole, Mandeville Isabel, Ribeiro Leslie, Ponton Andre, Martin James G, Kho Alvin T, Chu Jen-Hwa, Tantisira Kelan, Weiss Scott T, Raby Benjamin A, Kaplan Feige
Abstract excerpt
Asthma is the leading serious pediatric chronic illness in the United States, affecting 7.1 million children. The prevalence of asthma in children under 4 years of age has increased dramatically in the last 2 decades. Existing evidence suggests that this increase in prevalence derives from early environmental exposures acting on a pre-existing asthma-susceptible genotype. We studied the origins of asthma...
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