Article
Functional analysis of the sortase YhcS in Bacillus subtilis.
Proteomics - 1 Oct 2011
Fasehee Hamidreza, Westers Helga, Bolhuis Albert, Antelmann Haike, Hecker Michael, Quax Wim J, Mirlohi Agha F, van Dijl Jan Maareten, Ahmadian Gholamreza
Abstract excerpt
Sortases of Gram-positive bacteria catalyze the covalent C-terminal anchoring of proteins to the cell wall. Bacillus subtilis, a well-known host organism for protein production, contains two putative sortases named YhcS and YwpE. The present studies were aimed at investigating the possible sortase function of these proteins in B. subtilis. Proteomics analyses revealed that sortase-mutant cells released elevated...
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