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Article

FXIII-A Leu34 genetic variant in premature coronary artery disease: a genotype--phenotype case control study.

Thrombosis and haemostasis - 1 Sept 2011

Silvain Johanne, Pena Ana, Vignalou Jean-Baptiste, Hulot Jean-Sébastien, Galier Sophie, Cayla Guillaume, Bellemain-Appaix Anne, Barthélémy Olivier, Beygui Farzin, Bal-dit-Sollier Claire, Drouet Ludovic, Weisel John W, Montalescot Gilles, Collet Jean-Phillippe

Abstract excerpt

The FXIII-A Leu34 genetic variant increases and accelerates fibrin stabilisation; however, its association with premature coronary artery disease (CAD) and thrombotic events remains controversial. FXIII Val34Leu genotype was determined in 242 young individuals (<45 years old) who survived a myocardial infarction (MI) and 242 healthy controls matched for age and gender. We evaluated its effect on long-term...

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Identifiers

PMID: 21800001
DOI: 10.1160/TH11-01-0027
PMCID: PMC3343691

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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