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Article

Factor XIII-A subunit Val34Leu polymorphism in fatal atherothrombotic ischemic stroke.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jun 2014

Shemirani Amir-Houshang, Antalfi Bálint, Pongrácz Endre, Mezei Zoltán András, Bereczky Zsuzsanna, Csiki Zoltán

Abstract excerpt

Factor XIII (FXIII) is a regulator of fibrinolysis and clot firmness. Val34Leu polymorphism of its potentially active A subunit (FXIII-A) leads to faster activation of FXIII, influences clot structure and provides a moderate protection against coronary artery disease. The effect of FXIII-A Val34Leu polymorphism on the risk of atherothrombotic ischemic stroke (AIS) has been investigated in a few studies with...

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PMID: 24686102
DOI: 10.1097/MBC.0000000000000055

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