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Early Events in Herpes Simplex Virus Lifecycle with Implications for an Infection of Lifetime

19 Jan 2012

Abstract excerpt

Affecting a large percentage of human population herpes simplex virus (HSV) types -1 and -2 mainly cause oral, ocular, and genital diseases. Infection begins with viral entry into a host cell, which may be preceded by viral "surfing" along filopodia. Viral glycoproteins then bind to one or more of several cell surface receptors, such as herpesvirus entry mediator (HVEM), nectin-1, 3-O sulfated heparan sulfate...

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PMID: 22291864
DOI: 10.2174/1874357901206010001

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