Article
An important role for syndecan-1 in herpes simplex virus type-1 induced cell-to-cell fusion and virus spread.
PloS one - 1 Jan 2011
Karasneh Ghadah A, Ali Mohamed, Shukla Deepak
Abstract excerpt
Herpes simplex virus type-1 (HSV-1) is a common human pathogen that relies heavily on cell-to-cell spread for establishing a lifelong latent infection. Molecular aspects of HSV-1 entry into host cells have been well studied; however, the molecular details of the spread of the virus from cell-to-cell remain poorly understood. In the past, the role of heparan sulfate proteoglycans (HSPG) during HSV-1 infection has...
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