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Article

Genetic variation in phosphodiesterase (PDE) 7B in chronic lymphocytic leukemia: overview of genetic variants of cyclic nucleotide PDEs in human disease.

Journal of human genetics - 1 Sept 2011

Peiró Ana M, Tang Chih-Min, Murray Fiona, Zhang Lingzhi, Brown Loren M, Chou Daisy, Rassenti Laura, Kipps Thomas J, Kipps Thomas A, Insel Paul A

Abstract excerpt

Expression of cyclic adenosine monophosphate-specific phosphodiesterase 7B (PDE7B) mRNA is increased in patients with chronic lymphocytic leukemia (CLL), thus suggesting that variation may occur in the PDE7B gene in CLL. As genetic variation in other PDE family members has been shown to associate with numerous clinical disorders (reviewed in this manuscript), we sought to identify single-nucleotide polymorphisms...

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Identifiers

PMID: 21796143
DOI: 10.1038/jhg.2011.80
PMCID: PMC3833258

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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