Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic association study of phosphodiesterase 8B gene with subclinical hypothyroidism in pregnant women.

Endocrine research - 1 Jan 2015

Yang Shuai, Tao Jun, Zhang Junyu, Fan Jianxia, Qian Wei, Shu Khor

Abstract excerpt

OBJECTIVE: To explore whether phosphodiesterase 8B (PDE8B) gene is involved in the etiology of subclinical hypothyroidism (SCH) in pregnant women. METHODS: A total of 180 pregnant patients with SCH and 311 healthy, pregnant control subjects were recruited in this study to detect 4 (rs4704397, rs6885099, rs2046045, and rs12514694 in PDE8B) single nucleotide polymorphisms (SNPs). Univariate associations were...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3',5'-Cyclic-AMP Phosphodiesterases
Share to Genetic Association Studies
Share to Genotype
Share to Hypothyroidism
Share to Polymorphism, Single Nucleotide
Share to Pregnancy
Share to Pregnancy Complications

Source

Identifiers

PMID: 25822812
DOI: 10.3109/07435800.2015.1015728

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic association study of phosphodiesterase 8B gene with subclinical hypothyroidism in pregnant women.PMID 25822812Read ↗

Phosphodiesterase 8B gene polymorphism is associated with subclinical hypothyroidism in pregnancy.Semantic proximity Read ↗

[Association analysis of PDE8B gene polymorphisms with the susceptibility to Hyperthyroxinemia in Chinese Han population].Semantic proximity Read ↗

Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function.Semantic proximity Read ↗

Phosphodiesterase 8B gene polymorphism in women with recurrent miscarriage: a retrospective case control study.Semantic proximity Read ↗

Genome-wide association studies of thyroid-related hormones, dysfunction, and autoimmunity among 85,421 Chinese pregnancies.Semantic proximity Read ↗

Haplotype analysis of the promoter region of phosphodiesterase type 8B (PDE8B) in correlation with inactivating PDE8B mutation and the serum thyroid-stimulating hormone levels.Semantic proximity Read ↗

Genetic associations with neonatal thyroid-stimulating hormone levels.Semantic proximity Read ↗

Frequency and effect on serum TSH of phosphodiesterase 8B (PDE8B) gene polymorphisms in patients with sporadic nonautoimmune subclinical hypothyroidism.Semantic proximity Read ↗

Impact of phosphodiesterase 8B gene rs4704397 variation on thyroid homeostasis in childhood obesity.Semantic proximity Read ↗

Association study of PDE4B with panic disorder in the Japanese population.Semantic proximity Read ↗

Initial screening of the rs104893657 variant of the PAX8 gene in women with hypothyroidism from Northeastern Slovakia.Semantic proximity Read ↗

Reference values and the effect of clinical parameters on thyroid hormone levels during early pregnancySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.