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Article

Global cellular changes induced by Legionella pneumophila infection of bone marrow-derived macrophages.

Immunobiology - 1 Dec 2011

Fortier Anne, Faucher Sebastien P, Diallo Kanny, Gros Philippe

Abstract excerpt

The nucleotide-binding oligomerization domain (Nod)-like receptor (NLR) family member Naip5 plays an essential role in restricting Legionella pneumophila growth inside primary macrophages. Upon interaction with bacterial flagellin, the intracellular receptor Naip5 forms a multi-protein complex, the inflammasome, which activation has a protective role against infection. The A/J mouse strain carries a Naip5 allele...

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Source

Identifiers

PMID: 21794945
DOI: 10.1016/j.imbio.2011.06.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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