Article
Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia.
Haematologica - 1 Oct 2011
Balgobind Brian V, Hollink Iris H I M, Arentsen-Peters Susan T C J M, Zimmermann Martin, Harbott Jochen, Beverloo H Berna, von Bergh Anne R M, Cloos Jacqueline, Kaspers Gertjan J L, de Haas Valerie, Zemanova Zuzana, Stary Jan, Cayuela Jean-Michel, Baruchel Andre, Creutzig Ursula, Reinhardt Dirk, Pieters Rob, Zwaan C Michel, van den Heuvel-Eibrink Marry M
Abstract excerpt
BACKGROUND: Several studies of pediatric acute myeloid leukemia have described the various type-I or type-II aberrations and their relationship with clinical outcome. However, there has been no recent comprehensive overview of these genetic aberrations in one large pediatric acute myeloid leukemia cohort. DESIGN AND METHODS: We studied the different genetic aberrations, their associations and their impact on...
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