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Article

Cytogenetic, molecular genetic, and clinical characteristics of acute myeloid leukemia with a complex karyotype.

Seminars in oncology - 1 Aug 2008

Mrózek Krzysztof

Abstract excerpt

Patients with acute myeloid leukemia (AML) harboring three or more acquired chromosome aberrations in the absence of the prognostically favorable t(8;21)(q22;q22), inv(16)(p13q22)/t(6;16)(p13;q22), and t(15;17)(q22;q21) aberrations form a separate category - AML with a complex karyotype. They constitute 10% to 12% of all AML patents, with the incidence of complex karyotypes increasing with the more advanced age....

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Topics

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Share to Chromosome Aberrations
Share to CDX2 gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ETV6 gene

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Share to Leukemia, Myeloid, Acute

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Source

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Identifiers

PMID: 18692687
DOI: 10.1053/j.seminoncol.2008.04.007
PMCID: PMC3640813

Genes

APP
CDX2
CTNNA1
DDX6
ERG
ETS1
ETS2
ETV6
FLI1
GAB2
MYC
TCF4
TRIB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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