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Article

Relative abundance of EGFR mutations predicts benefit from gefitinib treatment for advanced non-small-cell lung cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Aug 2011

Zhou Qing, Zhang Xu-Chao, Chen Zhi-Hong, Yin Xiao-Lu, Yang Jin-Ji, Xu Chong-Rui, Yan Hong-Hong, Chen Hua-Jun, Su Jian, Zhong Wen-Zhao, Yang Xue-Ning, An She-Juan, Wang Bin-Chao, Huang Yi-Sheng, Wang Zhen, Wu Yi-Long

Abstract excerpt

PURPOSE: Our aim was to determine whether abundance of epidermal growth factor receptor (EGFR) mutations in tumors predicts benefit from treatment with EGFR-tyrosine kinase inhibitors (TKIs) for advanced non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS: We detected EGFR mutations in 100 lung cancer samples using direct DNA sequencing and amplification refractory mutation system (ARMS). Mutation-positive...

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Source

Identifiers

PMID: 21788562
DOI: 10.1200/JCO.2010.33.3757

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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