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Article

[Detection and Clinical Significance of Abundance of EGFR Mutation].

Zhongguo fei ai za zhi = Chinese journal of lung cancer - 20 Aug 2017

Shao Yi, Zhong Diansheng

Abstract excerpt

Non-small cell lung cancer (NSCLC) patients, with sensitive epidermal growth factor receptor (EGFR) mutations react well to tyrosine kinase inhibitors (TKIs). However, the efficacy of TKIs on patients with the same mutant types differs dramatically. It is implied that the different quantities of mutant alleles could be one of the reasons underlying. Patients with high abundance of EGFR mutation might benefit more...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28855040
DOI: 10.3779/j.issn.1009-3419.2017.08.13
PMCID: PMC5973003

Genes

EGFR

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