Article
Regulation of the human neurotropic virus promoter by JCV-T antigen and HIV-1 tat protein.
Oncogene - 1 Dec 1990
Chowdhury M, Taylor J P, Tada H, Rappaport J, Wong-Staal F, Amini S, Khalili K
Abstract excerpt
We compared the ability of HIV-1 tat protein and JCV T-antigen in inducing transcription from the JCV late promoter, JCVL. A JCVL promoter-chloramphenicol acetyltransferase plasmid (pJCL-CAT) was transfected into human glial cells alone or together with plasmids producing T-antigen and tat protei...
Topics
- Antigens, Polyomavirus Transforming
- Base Sequence
- Chloramphenicol O-Acetyltransferase
- Chromosome Deletion
- Gene Expression Regulation, Viral
- Gene Products, tat
- HIV-1
- Humans
- JC Virus
- Molecular Sequence Data
- Mutation
- Neuroglia
- Plasmids
- Promoter Regions, Genetic
- Transcription, Genetic
- Transfection
- tat Gene Products, Human Immunodeficiency Virus