Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Potential Mechanisms of the Human Polyomavirus JC in Neural Oncogenesis

1 Aug 2008

Abstract excerpt

The human polyomavirus JC (JCV) is a small DNA tumor virus and the etiologic agent of the progressive multifocal leukoencephalopathy. In progressive multifocal leukoencephalopathy, active JCV replication causes the lytic destruction of oligodendrocytes. The normal immune system prevents JCV replication and suppresses the virus into a state of latency so that expression of viral proteins cannot be detected. In a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antenna Design and Analysis
Share to Full-Duplex Wireless Communications
Share to Polyomavirus and related diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18648329
DOI: 10.1097/nen.0b013e318180e631

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Potential Mechanisms of the Human Polyomavirus JC in Neural OncogenesisPMID 18648329Read ↗

The Role of the JC Virus in Central Nervous System Tumorigenesis.Semantic proximity Read ↗

Human neurotropic polyomavirus, JCV, and its role in carcinogenesis.Semantic proximity Read ↗

Review on the role of the human Polyomavirus JC in the development of tumorsSemantic proximity Read ↗

JC polyomavirus in the aetiology and pathophysiology of glial tumours.Semantic proximity Read ↗

Primary Central Nervous System Lymphoma Expressing the Human Neurotropic Polyomavirus, JC Virus, GenomeSemantic proximity Read ↗

The oncogenic roles of JC polyomavirus in cancerSemantic proximity Read ↗

Progressive Multifocal Leukoencephalopathy: Molecular Biology, Pathogenesis and Clinical ImpactSemantic proximity Read ↗

Polyomavirus JC in the context of immunosuppression: a series of adaptive, DNA replication-driven recombination events in the development of progressive multifocal leukoencephalopathy.Semantic proximity Read ↗

Expression of Human Neurotropic Polyomavirus JCV Late Gene Product Agnoprotein in Human MedulloblastomaSemantic proximity Read ↗

Progressive Multifocal Leukoencephalopathy: Endemic Viruses and Lethal Brain DiseaseSemantic proximity Read ↗

Expression of JC virus regulatory proteins in human cancer: potential mechanisms for tumourigenesis.Semantic proximity Read ↗

JC polyomavirus: a short review of its biology, its association with progressive multifocal leukoencephalopathy, and the diagnostic value of different methods to manifest its activity or presence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.