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Article

No association between polymorphisms in cubilin, a gene of the homocysteine metabolism and the risk of non-syndromic cleft lip with or without cleft palate.

International journal of immunopathology and pharmacology - 1 Jan 2000

Martinelli M, Carinci F, Morselli P G, Palmieri A, Girardi A, Riberti C, Scapoli L

Abstract excerpt

Epidemiological studies have correlated lower maternal periconceptional levels of plasma folate and cobalamin with increased risk of delivering offspring presenting congenital malformations such as cleft lip with or without cleft palate (CL/P) or neural tube defects. A number of genetic studies aimed at correlating these biochemical levels or the occurrence of malformations with specific genetic defects or...

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Source

Identifiers

PMID: 21781439
DOI: 10.1177/03946320110240S203

Genes

CUBN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

No association between polymorphisms in cubilin, a gene of the homocysteine metabolism and the risk of non-syndromic cleft lip with or without cleft palate.PMID 21781439Read ↗

An association study of 45 folate-related genes in spina bifida: Involvement of cubilin (CUBN) and tRNA aspartic acid methyltransferase 1 (TRDMT1).Semantic proximity Read ↗

Non-syndromic cleft palate: Association analysis on three gene polymorphisms of the folate pathway in Asian and Italian populations.Semantic proximity Read ↗

Vitamin B12 Transport Genes and Nonsyndromic Cleft Lip With or Without Cleft Palate in Chile.Semantic proximity Read ↗

RFC1 and non-syndromic cleft lip with or without cleft palate: an association based study in Italy.Semantic proximity Read ↗

Non-syndromic cleft lip with or without cleft palate in Asian populations: Association analysis on three gene polymorphisms of the folate pathway.Semantic proximity Read ↗

Genetic Variants in Folate and Cobalamin Metabolism-Related Genes in Pregnant Women of a Homogeneous Spanish Population: The Need for Revisiting the Current Vitamin Supplementation Strategies.Semantic proximity Read ↗

Novel CUBN Mutation in a Young Child With Megaloblastic Anemia.Semantic proximity Read ↗

Mutations in CUBN, encoding the intrinsic factor-vitamin B12 receptor, cubilin, cause hereditary megaloblastic anaemia 1.Semantic proximity Read ↗

New evidence for the role of cystathionine beta-synthase in non-syndromic cleft lip with or without cleft palate.Semantic proximity Read ↗

The MTHFD1 gene is not involved in cleft lip with or without palate onset among the Italian population.Semantic proximity Read ↗

A frameshift mutation in the cubilin gene (<i><scp>CUBN</scp></i>) in <scp>B</scp>eagles with <scp>I</scp>merslund–<scp>G</scp>räsbeck syndrome (selective cobalamin malabsorption)Semantic proximity Read ↗

No evidence for a role of CRISPLD2 in non-syndromic cleft lip with or without cleft palate in an Italian population.Semantic proximity Read ↗

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