Behavioral and molecular genetics of dissociation: the role of the serotonin transporter gene promoter polymorphism (5-HTTLPR).

doi:10.1002/jts.20659

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Article

Behavioral and molecular genetics of dissociation: the role of the serotonin transporter gene promoter polymorphism (5-HTTLPR).

Journal of traumatic stress - 1 Aug 2011

Pieper Suzanne, Out Dorothée, Bakermans-Kranenburg Marian J, van Ijzendoorn Marinus H

Abstract excerpt

We evaluated the role of the serotonin transporter gene promoter polymorphism (5-HTTLPR) in the etiology of dissociation. Adult twin pairs (N = 184 pairs; mean age 33.0 years, SD = 10.8) completed measures for dissociation and trauma. The DNA samples were genotyped for 5-HTTLPR adjusted for rs25531 alleles. Behavioral genetic analyses showed that genetic factors explained 45% of the variance in dissociative...

Topics

Adult
Aged
Alleles
Behavior
Dissociative Disorders
Female
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Biology

Netherlands

Polymorphism, Genetic

Sequence Analysis, DNA

Serotonin Plasma Membrane Transport Proteins

Young Adult

Source

Open in PubMed

Identifiers

PMID: 21780190
DOI: 10.1002/jts.20659

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-21780190-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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