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Article

P53 codon 72 (Arg72Pro) polymorphism and prostate cancer risk: association between disease onset and proline genotype.

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2011

Rogler Anja, Rogenhofer Michael, Borchardt Albert, Lunz Jens-Claudio, Knoell Antje, Hofstaedter Ferdinand, Tannapfel Andrea, Wieland Wolf, Hartmann Arndt, Stoehr Robert

Abstract excerpt

The tumor suppressor gene p53 plays an important role in the stress response of the cell and is mutated in 50% of all human tumors. The p53 Arg72Pro single-nucleotide polymorphism (SNP) was found to be associated with an increased risk of various malignancies. Biochemical and biological differences between the 2 polymorphic variants of wild-type P53 might lead to distinct susceptibility to HPV- and...

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Identifiers

PMID: 21778786
DOI: 10.1159/000326767

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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