Article
Association of codon 72 polymorphism of p53 with lower prostate cancer risk.
The Prostate - 1 Dec 2001
Henner W D, Evans A J, Hough K M, Harris E L, Lowe B A, Beer T M
Abstract excerpt
BACKGROUND: A common germline polymorphism of p53 produces a protein with an Arg to Pro change at codon 72. This Pro variant has altered biochemical properties suggesting altered cancer susceptibility. METHODS: A case control study with 115 men with prostate cancer and 181 community control male subjects was conducted. Demographics, family history of cancer, and blood were obtained. Codon 72 genotypes were...
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