Article
Does p53 codon 72 polymorphism have a prognostic value in carcinoma of the vulva and vagina?
Medical oncology (Northwood, London, England) - 1 Mar 2017
Qvick Alvida, Sorbe Bengt, Helenius Gisela, Karlsson Mats G, Lillsunde Larsson Gabriella
Abstract excerpt
Human papilloma virus (HPV) is considered to be responsible for a large part of vaginal and vulvar carcinomas, and the p53 codon 72 polymorphism has been implicated in susceptibility to cancer induced by this virus, but with contradicting results. In this study, we have investigated the prognostic value of the codon 72 polymorphism by real-time PCR (qPCR) in two cohorts of vaginal (n = 66) and vulvar (n = 123)...
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