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Article

Esco2 promotes neuronal differentiation by repressing Notch signaling.

Cellular signalling - 1 Nov 2011

Leem Young-Eun, Choi Hyun-Kyung, Jung Sung Yun, Kim Beom-Jun, Lee Ki-Young, Yoon Keejung, Qin Jun, Kang Jong-Sun, Kim Seong-Tae

Abstract excerpt

Esco2 is an acetyltransferase that is required for the establishment of sister chromatid cohesion. Roberts-SC phocomelia (RBS) syndrome caused by the mutations of Esco2 gene, is an autosomal recessive development disorder characterized by growth retardation, limb reduction and craniofacial abnormalities including cleft lip and palate. Here, we show that Esco2 protein co-immunoprecipitates with Notch but not with...

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Source

Identifiers

PMID: 21777673
DOI: 10.1016/j.cellsig.2011.07.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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