Article
Influence of aldosterone synthase gene C-344T polymorphism on focal segmental glomerulosclerosis.
Nephrology (Carlton, Vic.) - 1 Nov 2011
Bantis Christos, Heering Peter J, Stangou Maria, Kouri Nicoletta-Maria, Schwandt Christina, Memmos Dimitrios, Rump Lars-Christian, Ivens Katrin
Abstract excerpt
AIM: We evaluated the influence of C-344T polymorphism of the aldosterone synthase gene, associated with aldosterone levels and the development of arterial hypertension, on focal segmental glomerulosclerosis (FSGS). METHODS: We studied 81 patients with primary FSGS followed up for 8.0 ± 12 years. Patients were classified according to their slope of reciprocal serum creatinine into group A (slow progressors, n =...
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