Article
Genetic polymorphisms of renin-angiotensin system and progression of interstitial nephritis.
Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina - 1 Jan 2002
Buraczyńska Monika, Grzebalska Agnieszka, Spasiewicz Danuta, Orłowska Grazyna, Ksiazek Andrzej
Abstract excerpt
Genes of the renin-angiotensin system (RAS) are involved in the progression of renal failure. Among them, the angiotensin-converting enzyme (ACE), angiotensinogen (AGT) and angiotensin II type 1 receptor (AT1R) genes are of particular interest. We examined polymorphisms of these three genes for association with the development of interstitial nephritis and progression to end-stage renal failure. The allele...
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