Article
Methylenetetrahydrofolate reductase polymorphism in childhood primary focal segmental glomerulosclerosis.
Nephron - 1 Oct 2002
Zou Chaochun, Tsukahara Hirokazu, Hiraoka Masahiro, Mizu Jiang, Todoroki Yukiko, Ohshima Yusei, Kimura Hideki, Tsuzuki Kazuo, Mayumi Mitsufumi
Abstract excerpt
AIM: The purpose of this study was to evaluate the association between the methylenetetrahydrofolate reductase (MTHFR) C/T polymorphism and the prevalence and course of focal segmental glomerulosclerosis (FSGS) in our pediatric population. METHODS: Genotypes for MTHFR were determined in 15 primary FSGS patients (male/female, 6/9) and 238 control subjects (male/female, 110/128) by the polymerase chain reaction and...
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