Article
Association of aldosterone synthase (CYP11B2) gene -344T/C polymorphism with the risk of primary chronic glomerulonephritis in the Polish population.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Dec 2014
Pawlik Magdalena, Mostowska Adrianna, Lianeri Margarita, Oko Andrzej, Jagodziński Paweł P
Abstract excerpt
INTRODUCTION: We evaluate whether angiotensinogen AGT M235T (rs699), angiotensin-converting enzyme ACE (I/D) (rs4646994) and aldosterone synthase CYP11B2 -344C/T (rs1799998) polymorphisms can be genetic risk factors of chronic glomerulonephritis (GN) in the Polish population. MATERIALS AND METHODS: The study was conducted in 140 patients with primary chronic GN: mesangial proliferative GN (MesPGN) (n = 49), IgA...
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