Article
Effects of the genetic polymorphisms of the renin-angiotensin system on focal segmental glomerulosclerosis.
Kidney & blood pressure research - 1 Jan 2003
Luther Y, Bantis C, Ivens K, Fehsel K, Kolb-Bachhofen V, Heering P
Abstract excerpt
BACKGROUND/AIMS: We analyzed the influence of angiotensin-converting enzyme (ACE) I/D, angiotensinogen (AGT) M235T and angiotensin-II-type-1 receptor (AT1R) A1166C genetic polymorphisms on the clinical course of focal segmental glomerulosclerosis (FSGS). METHODS: This study consisted of 71 patients with nephrotic syndrome due to biopsy proven FSGS and 100 healthy controls. According to the slope of the reciprocal...
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