Article
A conserved long noncoding RNA affects sleep behavior in Drosophila.
Genetics - 1 Oct 2011
Soshnev Alexey A, Ishimoto Hiroshi, McAllister Bryant F, Li Xingguo, Wehling Misty D, Kitamoto Toshihiro, Geyer Pamela K
Abstract excerpt
Metazoan genomes encode an abundant collection of mRNA-like, long noncoding (lnc)RNAs. Although lncRNAs greatly expand the transcriptional repertoire, we have a limited understanding of how these RNAs contribute to developmental regulation. Here, we investigate the function of the Drosophila lncRNA called yellow-achaete intergenic RNA (yar). Comparative sequence analyses show that the yar gene is conserved in...
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