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Article

Identification of Redeye, a new sleep-regulating protein whose expression is modulated by sleep amount.

eLife - 1 Jan 2014

Shi Mi, Yue Zhifeng, Kuryatov Alexandre, Lindstrom Jon M, Sehgal Amita

Abstract excerpt

In this study, we report a new protein involved in the homeostatic regulation of sleep in Drosophila. We conducted a forward genetic screen of chemically mutagenized flies to identify short-sleeping mutants and found one, redeye (rye) that shows a severe reduction of sleep length. Cloning of rye reveals that it encodes a nicotinic acetylcholine receptor α subunit required for Drosophila sleep. Levels of RYE...

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Identifiers

PMID: 24497543
DOI: 10.7554/eLife.01473
PMCID: PMC3912633

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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