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Article

An interaction between Nrf2 polymorphisms and smoking status affects annual decline in FEV1: a longitudinal retrospective cohort study.

BMC medical genetics - 20 Jul 2011

Masuko Hironori, Sakamoto Tohru, Kaneko Yoshiko, Iijima Hiroaki, Naito Takashi, Noguchi Emiko, Hirota Tomomitsu, Tamari Mayumi, Hizawa Nobuyuki

Abstract excerpt

BACKGROUND: An Nrf2-dependent response is a central protective mechanism against oxidative stress. We propose that particular genetic variants of the Nrf2 gene may be associated with a rapid forced expiratory volume in one second (FEV1) decline induced by cigarette smoking. METHODS: We conducted...

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Identifiers

PMID: 21774808
DOI: 10.1186/1471-2350-12-97
PMCID: PMC3160350

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21774808-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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