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Article

A pharmacogenomic method for individualized prediction of drug sensitivity.

Molecular systems biology - 19 Jul 2011

Cohen Adam L, Soldi Raffaella, Zhang Haiyu, Gustafson Adam M, Wilcox Ryan, Welm Bryan E, Chang Jeffrey T, Johnson Evan, Spira Avrum, Jeffrey Stefanie S, Bild Andrea H

Abstract excerpt

Identifying the best drug for each cancer patient requires an efficient individualized strategy. We present MATCH (Merging genomic and pharmacologic Analyses for Therapy CHoice), an approach using public genomic resources and drug testing of fresh tumor samples to link drugs to patients. Valproic acid (VPA) is highlighted as a proof-of-principle. In order to predict specific tumor types with high probability of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21772261
DOI: 10.1038/msb.2011.47
PMCID: PMC3159972

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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