Article

CRISPR targeting of H3K4me3 activates gene expression and unlocks centromere-proximal crossover recombination in Arabidopsis

2025-02-08

Abstract excerpt

<h4>ABSTRACT</h4> H3K4me3 is a fundamental and highly conserved chromatin mark across eukaryotes, playing a central role in many genome-related processes, including transcription, maintenance of cell identity, DNA damage repair, and meiotic recombination. However, identifying the causal function of H3K4me3 in these diverse pathways remains a challenge, and we lack the tools to manipulate it for agricultural benef...

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Literature Corpus work: e769aefd-55a9-5c62-9113-df4deb82b1f8
DOI: 10.1101/2025.02.07.636860

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