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Article

A common RNA structural motif involved in the internal initiation of translation of cellular mRNAs

15 Jan 1997

Abstract excerpt

The 5'-non-translated regions (5'NTR) of human immunoglobulin heavy chain binding protein (BiP), Antennapedia (Antp) ofDrosophilaand human fibroblast growth factor 2 (FGF-2) mRNAs are reported to mediate translation initiation by an internal ribosome binding mechanism. In this study, we investigate predicted features of the higher order structures folded in these 5'NTR sequences. Statistical analyses of RNA...

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PMID: 9016566
DOI: 10.1093/nar/25.2.362

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