Article
Translation initiation modeling and mutational analysis based on the 3(')-end of the Escherichia coli 16S rRNA sequence.
Bio Systems - 1 Apr 2009
Dawy Zaher, Morcos Faruck, Weindl Johanna, Mueller Jakob C
Abstract excerpt
A model for the process of translation in gene expression is proposed. The model is based on the assumption that the ribosome decodes the mRNA sequences using consecutive subsequences of the 3(')-end of its 16S rRNA subunit. The biological consistency of the model is validated by successful detection of the Shine-Dalgarno signal and the start codon. Furthermore, implications on the role of the 3(')-end in the...
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