Article
HLA-B*27 subtypes and their implications in the pathogenesis of ankylosing spondylitis.
Gene - 5 Sept 2018
Dashti Navid, Mahmoudi Mahdi, Aslani Saeed, Jamshidi Ahmadreza
Abstract excerpt
Ankylosing spondylitis (AS) is a highly heritable kind of arthritis that affects the vertebral column. AS risk has been associated strongly with Human leukocyte antigen (HLA)-B*27. In fact, some HLA-B*27 subtypes have been associated with the increased disease risk, although some specific subtypes have not shown such associations. It is supposed that HLA-B*27 plays a major role in the etiopathogenesis of the...
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