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Article

Genetic study confirms association of HLA-DPA1(∗)01:03 subtype with ankylosing spondylitis in HLA-B27-positive populations.

Human immunology - 1 Jun 2013

Díaz-Peña Roberto, Castro-Santos Patricia, Aransay Ana M, Brüges-Armas Jacome, Pimentel-Santos Fernando M, López-Larrea Carlos

Abstract excerpt

The association of human leukocyte antigen (HLA)-B27 with ankylosing spondylitis (AS) has been known for over 38 years. However, it is not the only gene associated with AS. The aim of this study was to confirm the association of HLA markers around HLA-DPA1/DPB1 region with AS in HLA-B27 positive populations. Five SNPs (rs422544, rs6914849, rs92777535, rs3128968 and rs2295119) from the HLA-DPA1/DPB1 region were...

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Share to Alleles
Share to Case-Control Studies
Share to Gene Frequency
Share to HLA-B27 Antigen
Share to HLA-DP alpha-Chains
Share to HLA-DP beta-Chains
Share to Polymorphism, Single Nucleotide
Share to Spondylitis, Ankylosing

Source

Identifiers

PMID: 23459078
DOI: 10.1016/j.humimm.2013.02.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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