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Article

Association and treatment response to capecitabine-based chemoradiotherapy with CYP2C9 polymorphism in head and neck cancer.

Indian journal of cancer - 1 Jan 2000

Paul S, Pant M C, Parmar D, Verma J

Abstract excerpt

AIMS: The aim of the present study is to investigate the association of polymorphism in cytochrome P450 2C9 (CYP2C9) with head and neck squamous cell carcinoma (HNSCC) and response in patients receiving chemoradiotherapy. MATERIALS AND METHODS: One hundred ten males suffering from locally advanced head and neck squamous cell carcinoma and an equal number of healthy controls were genotyped for CYP2C9FNx012 and...

Topics

Antineoplastic Combined Chemotherapy Protocols
Aryl Hydrocarbon Hydroxylases
Brachytherapy
Carcinoma, Squamous Cell
Case-Control Studies
Chemoradiotherapy
Cytochrome P-450 CYP2C9
DNA
Follow-Up Studies
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Head and Neck Neoplasms

Humans

Male

Middle Aged

Neoplasm Staging

Polymerase Chain Reaction

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 21768671
DOI: 10.4103/0019-509X.82899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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