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Article

Association of poor metabolizers of cytochrome P450 2C19 with head and neck cancer and poor treatment response.

Mutation research - 26 Sept 2008

Yadav Sunishtha S, Ruwali Munindra, Shah Parag P, Mathur Neeraj, Singh Ram L, Pant Mohan C, Parmar Devendra

Abstract excerpt

A case-control study consisting of 300 patients and an equal number of healthy controls was carried out to investigate the association of polymorphism in cytochrome P450 2C19 (CYP2C19), which results in poor and extensive metabolizers (PMs and EMs) genotypes, with squamous cell carcinoma of head and neck (HNSCC) and treatment response in patients receiving combination of chemo-radiotherapy. A higher frequency of...

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Identifiers

PMID: 18644391
DOI: 10.1016/j.mrfmmm.2008.06.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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