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Article

Sidestream tobacco smoke is a male germ cell mutagen.

Proceedings of the National Academy of Sciences of the United States of America - 2 Aug 2011

Marchetti Francesco, Rowan-Carroll Andrea, Williams Andrew, Polyzos Aris, Berndt-Weis M Lynn, Yauk Carole L

Abstract excerpt

Active cigarette smoking increases oxidative damage, DNA adducts, DNA strand breaks, chromosomal aberrations, and heritable mutations in sperm. However, little is known regarding the effects of second-hand smoke on the male germ line. We show here that short-term exposure to mainstream tobacco smoke or sidestream tobacco smoke (STS), the main component of second-hand smoke, induces mutations at an expanded simple...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21768363
DOI: 10.1073/pnas.1106896108
PMCID: PMC3150936

Genes

STS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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