Article
Air pollution and mutations in the germline: are humans at risk?
Human genetics - 1 Mar 2009
Somers Christopher M, Cooper David N
Abstract excerpt
Genotoxic air pollution is ubiquitous in urban and industrial areas. A variety of studies has linked human exposure to air pollution with a number of different somatic cell endpoints including cancer. However, the potential for inducing mutations in the human germline remains unclear. Sentinel animal studies of germline mutations at tandem-repeat loci (specifically minisatellites and expanded simple tandem...
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