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Article

Combinatorial effect of TIMP-1 and α1AT gene polymorphisms on development of chronic obstructive pulmonary disease.

Clinical biochemistry - 1 Sept 2011

Kumar Manish, Bhadoria D P, Dutta Koushik, Singh Seema, Gupta Jyotsana, Kumar Ram, Chhillar Anil K, Yadav Vibha, Singh Bharat, Sharma G L

Abstract excerpt

OBJECTIVE: To study the role of α(1)AT and TIMP-1 gene polymorphisms in development of COPD. DESIGN AND METHODS: Blood samples from total 408 subjects (217 COPD patients and 191 controls) were used for genotyping and estimating biolevels of α(1)AT, TIMP-1 and inflammatory cytokines. Data was analyzed to determine the role of interaction of TIMP-1 and α(1)AT genes; and interplay between various genotypes and...

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Source

Identifiers

PMID: 21763297
DOI: 10.1016/j.clinbiochem.2011.06.986

Genes

PIM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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